Name 7 antimicrobials that should be avoided in patients with an allergy to sulfa antimicrobials. (Hint: all drug names include "sulfa" prefix)

1. Sulfamethoxazole (Bactrim)
2. Sulfamerazine
3. Sulfamethizole
4. Sulfamoxole
5. Sulfamethazine
6. Sulfoxazole
7. Sulfapyridine

Numbers 2 - 7 .... huh? Never heard of them. Looked 'em up and they don't seem to have a wide clinical utility and especially not in the emergency department. For my purposes in the ED, antimicrobial sulfa allergy = NO BACTRIM. There are sulfonamide NON-antimicrobials (including Furosemide, Bumetanide, Hydrochlorothiazide, Acetazolamide, Diazoxide, Sumatriptan, Alyburide, Celecoxib, Sulfasalazine) but the potential for cross reactivity between these drugs and sulfa antimicrobials is close to nil.


Source

Montanar, A. "Allergies to sulfonamide antibiotics and related drugs" Up to Date. 11 Feb 2009.
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