little white coats: Of the following clinical scenarios, choose the 2 where non-invasive ventilation (BIPAP, CPAP) has demonstrated the greatest efficacy.

neuromuscular disease
thoracic trauma
acute respiratory failure in asthma
end stage patients as palliative measure
extubation failure
copd exacerbations
cardiogenic pulmonary edema
obesity hypoventilation

While non-invasive ventilation has been used and demonstrated some efficacy in each of the above clinical scenarios, there is greatest evidence for success in those with copd exacerbations and cardiogenic pulmonary edema.

Source

Nava, S. and Hill, N. "Non-invasive ventilation in acute respiratory failure" Lancet. 18 July 2009.