If a patient becomes hypotensive after tPA for stroke and there is no obvious source of bleeding, what study should be done to look for a cause?

Echo to evaluate for tamponade. Rarely, patients who suffer stroke after a recent myocardial infarction can develop bleeding into the pericardium.


Source

Oliveira, J. et al. "Fibrinolytic therapy for acute ischemic stroke" Up to Date. 19 June 2009.