Prior to initiating post exposure prophylaxis for a sexual assault victim, which lab tests should be sent on the patient?

  • ELISA for HIV antibodies
  • Creatinine (Tenofovir-emtricitabine [Truvada] can cause nephrotoxicity)
  • LFTs (Zidovudine-lamivudine [Combivir] can cause abnormal LFTs, neutropenia, anemia)
  • CBC w/ diff
  • Anti-HBs antibodies
  • HBsAg
  • HCV antibodies
  • screening, including rapid plasma reagin (RPR), for other sexually transmitted infections
  • consider checking HIV viral load and HCV RNA if suspect that patient may have an acute HIV or Hep C infection

Source

Landovitz, R. and Currier. J. "Postexposure Prophylaxis for HIV Infection" New England Journal of Medicine. 29 Oct 2009.