Name two clinical scenarios where pyridoxine should be administered to control seizure activity?

1. isoniazid overdose 
2. neonatal status epilepticus, where pyridoxine deficiency is a rare cause of neonatal seizures

Source

UCSF Intensive Care Nursery House Staff Manual.  "Neonatal Seizures"  http://www.ucsfbenioffchildrens.org/pdf/manuals/48_Seizures.pdf

Romero, J.  and Kuczler, F.  "Isoniazid Overdose: Recognition and Management"  American Family Physician.  15 Feb 1998.

Sharieff, G.  and Hendry, P.  "Afebrile Pediatric Seizures"   Emerg Med Clin N Am.  2011.