Of the following clinical scenarios, choose the 2 where non-invasive ventilation (BIPAP, CPAP) has demonstrated the greatest efficacy.

• neuromuscular disease
• thoracic trauma
• acute respiratory failure in asthma
• end stage patients as palliative measure
  
• extubation failure
  
• copd exacerbations
• cardiogenic pulmonary edema
• obesity hypoventilation
  

While non-invasive ventilation has been used and demonstrated some efficacy in each of the above clinical scenarios, there is greatest evidence for success in those with copd exacerbations and cardiogenic pulmonary edema.


Source

Nava, S. and Hill, N. "Non-invasive ventilation in acute respiratory failure" Lancet. 18 July 2009.