Although the diagnosis of optic neuritis is often made on clinical grounds, gadolinium-enhanced MRI can help confirm the diagnosis. Optic nerve inflammation can be demonstrated in 95% of patient who have optic neuritis on gadolinium-enhanced MRI.
Source
Vortmann, M. and Schneider, J. "Acute Monocular Visual Loss" Emergency Medicine Clinics of North America. 2008.
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